| abstract |
Invention Patent: <B> "AMINOBUTYRIC ACID DERIVATIVES" <D>. A derivative of aminobutyric acid of formula (I) (where all symbols are as defined in the specification) and salts thereof. salts thereof. The compounds of formula (I) have inhibitory activity on matrix metalloproteinases and are useful for the prevention and / or treatment of diseases, for example, rheumatoid diseases, arthrosteitis, rare bone resorption, osteoporosis, periodontitis, interstitial nephritis, arteriosclerosis, pulmonary emphysema , cirrhosis, corneal injury, metastasis, invasion of or growth of tumor cells, autoimmune disease (eg, Crohn's disease, Sjogren's syndrome), diseases caused by vascular emigration or leukocyte infiltration, arterialization, multiple sclerosis, aneurysm of the aorta, endometriosis. |