| abstract |
Invention Patent: <B> "4-AMINO-2 (5H) -FURANONES AND 4-AMINO-2 (5H) -THREATING AND THIOURING DERIVATIVES AS ANTITUMORAL AGENTS" <D>. Objects of the present invention are compounds of the general formula (I), where A is oxygen or sulfur; X is oxygen or sulfur; R1 and R2 are, independently, hydrogen or an alkyl group having from 1 to 6 carbon atoms; R is selected from alkyl, cycloalkyl, alkylsulfinyl, alkylsulfonyl, hydroxyalkyl, naphthyl, phenyl group that can be unsubstituted or substituted; or R is a 5- or 6-membered heterocycle containing 1 to 3 heteroatoms selected from oxygen, sulfur and nitrogen, which can optionally be benzocondensed, pure stereoisomers or mixtures thereof as well as salts thereof with pharmaceutically acceptable acids or bases, for use as medicines, in particular as anti-tumor agents. |