| abstract |
"COMPOUND". The present invention encompasses structures of Formula (I) or their non-toxic pharmaceutically acceptable salts in which: X is hydrogen, halogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy or amino; and Y is substituted or unsubstituted alkyl, aryl or heteroaryl, the compounds of which are highly selective agonists, antagonists or inverse agonists for brain GABAa receptors or prodrugs of agonists, antagonists or inverse agonists for brain GABAa receptors. These compounds are usable in the diagnosis and treatment of anxiety, Down syndrome, sleep disorders, cognitive and seizure disorders and overdose with benzodiazepine medications and for enhancing agility. |