| abstract |
"COMPOUND, USE OF THE SAME, PHARMACEUTICAL COMPOSITION, AND, PROCESSES TO TREAT INFLAMMATORY CONDITIONS AND IMMUNOLOGICAL DISORDERS IN A PATIENT AND TO PREPARE A COMPOUND". A compound of formula (I) or a solvate thereof, wherein: X is -O- or -NH-; Q is (-CH ~ 2 ~ -) ~ p ~, (-CH = CH-) ~ p ~, (-C <154> C-) ~ p ~ where p is an integer from 0 to 4; R ^ 1 ^ is hydrogen or methyl; R ^ 2 ^ and R ^ 3 ^ independently represent O or S; n is an integer from 1 to 50; and R is hydrogen or methyl. This series of esters and complex amides of the selected phenyl xanthine derivatives inhibit the expression of adhesion molecules in the human umbilical endothelium vein cell (HUVEC) monolayers at very low concentrations and which are therefore indicated for the treatment of inflammatory conditions and immunological disorders. |