abstract |
"SULPHONAMIDES OF HETEROCYCLICAL THIOTHERS CONNECTED BY NITROGEN". This invention relates to neurotrophic sulfonamides of heterocyclic thioesters, with small molecules and low molecular weight, which have an affinity for immunophilins of the FKBP type, and their use as inhibitors of enzyme activity associated with immunophilin proteins, particularly enzyme activity peptidyl-prolyl-isomerase, or rotamase. |