abstract |
"ANALOGUES OF NUCLEOSìDEOS, AND, COMPOSITE". This invention relates to adenosine kinase inhibitors and nucleoside analogs, pyrrole [2,3-d] pyrimidine and pyrazol [3,4-d] pyrimidine modified nucleoside analogs, having activity as adenosine kinase inhibitors. The invention also concerns the preparation and use of these adenosine kinase inhibitors in the treatment of cardiovascular and cerebrovascular diseases, inflammation and other diseases that can be regulated by increasing the local concentration of adenosine. |