| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74b7b50944d8e1960440fb1f5440b7fd |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2799-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-03001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08 |
| filingDate |
2008-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d778d067748c65fc4ce2253896b7374
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cc2fe12991f198a53fafc905df7a4d2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92a5d84d54b029d24783781cb07504cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3baed6d657f9f49b0bd85cf36a34864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a909218df342ec2b5b5861b320761ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71571c3e4403b499d6124f3b5e10c7b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fd35156cb5867819bd872a1f69ae77a |
| publicationDate |
2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-122019000505-B1 |
| titleOfInvention |
BONE-TARGETED ALKALINE PHOSPHATASE, KITS AND METHODS OF ITS USE |
| abstract |
BONE-TARGETED ALKALINE OSPHATASE, KITS AND METHODS OF ITS USE. The present invention relates to a bone-targeting alkaline phosphatase, comprising a polypeptide having a structure: Z-sALP-Y-spacer-X-W n -V, wherein sALP is the extracellular domain of the alkaline phosphatase; wherein V is absent or an amino acid sequence of at least one amino acid; X is absent or is an amino acid sequence of at least one amino acid; Y is absent or an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; and W n is a polyaspartate or polyglutamate, where n = 10 to 16. Kits and methods of their use. |
| priorityDate |
2007-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |