| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10b81289cb0a3a34c6fcd4e4728ed5eb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-70 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate |
2021-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf5558c1408c8b6c751a55dc32f8e20d |
| publicationDate |
2023-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112022015863-A2 |
| titleOfInvention |
ISLET AMYLOID POLYPEPTIDE TARGETING PEPTIDE IMMUNOGENS (IAPP) FOR PREVENTION AND TREATMENT OF AGGREGATED IAPP-RELATED DISORDERS |
| abstract |
ISLET AMYLOID POLYPEPTIDE TARGETING PEPTIDE IMMUNOGENS (IAPP) FOR PREVENTION AND TREATMENT OF AGGREGATED IAPP-RELATED DISORDERS. The present disclosure relates to Islet Amyloid Polypeptide (IAPP) targeting peptide immunogen constructs, compositions containing the constructs, antibodies induced by the constructs, and methods of making and using the constructs and compositions thereof. The disclosed peptide immunogen constructs are greater than about 30 amino acids and contain (a) a B-cell epitope that is greater than about 6 contiguous amino acid residues from the IAPP aggregation-prone region of the full-length IAPP protein ; (b) a heterologous Th epitope; and (c) an optional heterologous spacer. The disclosed IAPP peptide immunogen constructs stimulate the generation of highly specific antibodies directed to IAPP for the prevention and/or treatment of disorders associated with aggregated IAPP. |
| priorityDate |
2020-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |