| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41686a979f961bce6a9855b4b409a5b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2025-0057
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2025-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2205-0205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-608
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-206
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M2210-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-204
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-114 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-049
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M25-0009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M25-0045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L29-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61M5-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L29-08 |
| filingDate |
2020-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22ec4e5f52b370763baee1e0b43dee56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8388dc16defbdc31c0b4b2bb8c96b99c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_518759533fff050d3af09eea31b6baf2 |
| publicationDate |
2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112022009621-A2 |
| titleOfInvention |
CHLORHEXIDINE AND NITRIC OXIDE RELEASE CATHETER FOR DUAL ANTIPLATETAL AND ANTIMICROBIAL FUNCTIONALITY |
| abstract |
CHLORHEXIDINE AND NITRIC OXIDE RELEASE CATHETER FOR DUAL ANTIPLATETAL AND ANTIMICROBIAL FUNCTIONALITY. A catheter configured to deliver nitric oxide and chlorhexidine providing antiplatelet and antimicrobial properties is manufactured by impregnating a thermoplastic polyurethane catheter extrusion with a nitric oxide releasing compound and with chlorhexidine. Thereafter, the impregnated catheter extrusion is coated with a polyurethane coating comprising chlorhexidine and/or nitric oxide releasing compound. In the impregnation step, the catheter extrusion may be exposed to a solvent having the nitric oxide releasing compound and chlorhexidine dissolved therein. Solvent is removed from the catheter extrusion. In the coating step, the impregnated catheter extrusion can be applied by immersion in a polymer solution comprising polyurethane and chlorhexidine and/or a nitric oxide releasing compound in a suitable solvent. The impregnated and/or coated nitric oxide releasing compound can be selected from s-nitroso-n-acetylpenicillamine (SNAP), s-nitroso glutathione (GSNO) and mixtures thereof. The impregnated and/or coated chlorhexidine can be selected from chlorhexidine diacetate, chlorhexidine base, chlorhexidine gluconate and mixtures thereof. |
| priorityDate |
2019-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |