| abstract |
composition, method of maintaining ether lipids, method of evaluating a subject, method of treatment or prevention, method of preventing asthma, and use of a composition. provided herein is a composition comprising a mixture of ether lipid molecules of formula (I), as defined herein. the composition serves for in vivo maintenance of ether lipids at levels and/or ratios associated with a non-diseased state, or wherein the composition serves for in vivo modification of ether lipids to levels and/or ratios associated with a state of non-disease. disease. also provided herein are methods of evaluating the subject for metabolic disease or dyslipidemia, comprising measuring the relative abundance of one or more lipid ether side chains in a biological sample from a subject, methods of preventing or treating disorders such as disease metabolic or dyslipidemia, or methods of preventing conditions such as obesity and asthma, particularly in infants, involving administration of a composition as defined herein. |