| titleOfInvention |
pharmaceutical composition, fusion protein, antibody that binds to human cd47, and, methods for treating a disease in a human subject, for increasing the selectivity of binding a monoclonal or bispecific antibody to human cd47, and for binding a cd47 antibody to cd47 human |
| abstract |
pharmaceutical composition, antibody that binds to human cd47, and, methods for treating a disease in a human subject, for increasing the binding selectivity of a monoclonal or bispecific antibody to human cd47, and for binding a cd47 antibody to human cd47. pharmaceutical compositions are provided, each comprising a glycosylation agent, an antibody that binds to human cd47, and a pharmaceutically acceptable carrier. novel cd47 antibodies that bind to human cd47 are also provided, wherein the antibodies bind to at least one epitope that is at one of the red blood cell cd47 protein glycosylation sites (e.g., at least one glycosylation site near the gln31 and thr34 epitope residues in cd47). |