Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-542 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 |
filingDate |
2019-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b6193dab283a9c17799bf82df94db99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7796493750f4d0281d2cd2460a3168c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6306986a5e28f55b49b9e8347125b058 |
publicationDate |
2021-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
BR-112021006782-A2 |
titleOfInvention |
tyrosine-tyrosine protein analogues and methods of using them |
abstract |
tyrosine-tyrosine protein analogues and methods of using them. The present invention relates to pyy analogs that include modifications that increase half-life when compared to native human pyy, as well as additional modifications that increase potency and selectivity at the npy2 receptor. also described are pharmaceutical compositions which include one or more of the pyy analogues described herein, in a pharmaceutically acceptable carrier. methods of making and using the pyy analogues are also described, especially for treating obesity, and obesity-related diseases and disorders such as type ii diabetes mellitus. |
priorityDate |
2018-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |