http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112021006597-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1567ae0f1a4843ae7bbef88fa8e1c534 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-50 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0066 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-68 |
| filingDate | 2019-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a0c6fc2c5bf265fa0879c1e02f756d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85cfe7677ccb07418496e168f108a124 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fb97b0b910f4e618cce0ccfbb085548 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9387dd4b871e61d93503abe5b6e269f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e092fe43bc82d949da938a241f88cae1 |
| publicationDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-112021006597-A2 |
| titleOfInvention | DNA plasmid, bacterial host cell, use of a nucleotide sequence, methods to reduce recombination of a DNA plasmid and to produce a polyribonucleotide, polyribonucleotide, and pharmaceutical composition |
| abstract | DNA plasmid, bacterial host cell, use of a nucleotide sequence, methods to reduce recombination of a DNA plasmid and to produce a polyribonucleotide, polyribonucleotide, and, pharmaceutical composition. the present description provides a DNA plasmid comprising a sequence encoding an mRNA molecule and a modified poly(a) tail, wherein the part of the sequence encoding the modified poly(a) tail is distinguished in that it consists of at least two a elements, each defined as a nucleotide sequence consisting of 55 to 65 nucleotides and at least one s element, each s element consisting of a nucleotide that is not a t nucleotide or 2 to 10 nucleotides, preferably 6 nucleotides, where each of the two terminal nucleotides is not a t nucleotide, where the number of a elements is greater than the number of s elements, where any two a elements are separated by an s element; said DNA plasmid exhibiting reduced recombination during amplification in a bacterial host cell compared to the same DNA plasmid without said at least one s element. |
| priorityDate | 2018-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1233.