| abstract |
compound and pharmaceutical composition. the invention relates to compounds or their pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates. the pharmaceutical compositions comprise an effective amount of compounds of formula I, formula ii, formula iii, formula iv, formula v and formula vi, and methods for treating eye disorders and skin diseases, and may be formulated for topical eye drops, topical paste, eye solution, device drug delivery, oral administration, buccal, rectal, topical, transdermal, transmucosal, by tablet, by spray, by intravenous solution, oral, by nasal spray, by oral solution, cream, dermal ointment, gels, lotions, suspension, oral spray, per oral mucosal layer tablet, parenteral, syrup or injection. such compositions can be used for the treatment of skin diseases such as acne, rosacea, and eye disorders such as eye redness, glaucoma, presbyopia, pyo, cataract, dry eye and ogvhd. |