| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63f37013aef4f4a6c303895001381758 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-417
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 |
| filingDate |
2019-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d8fcd58135a420f9dacc465c4a76d56 |
| publicationDate |
2021-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112021003147-A2 |
| titleOfInvention |
zinc complex, production and use of it |
| abstract |
"zinc complex, production and use of it". The present invention relates to a novel complex of zinc with gamma-1-glutamylhistamine with a metal/binder ratio of 1/1. in particular, the invention relates to a compound of formula (I). the complex according to the invention helps to restore the barrier functions of epithelial tissue and suppress aberrant immune cell activity. the invention also relates to the method of producing complexes and use of said zinc complex for the treatment of atopic dermatitis and other diseases associated with impaired barrier functions of the epithelial tissue and the development of an aberrant inflammatory response. the invention also relates to the use of the prepared complex to inhibit glutaminyl cyclase. this invention also relates to pharmaceutical compositions comprising a therapeutically effective amount of a compound of the invention. (i) |
| priorityDate |
2018-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |