| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70578
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001129
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2827 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68f7bca8e9052132e2a8078381760012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ca7f509a04186b233fc1a6152aad15d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_029aaac40c442f32f7c54d5ff040c292
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31d66662f7963f7d814e614ce2beff55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dac415f7220eaaa67a750d6bd3b739c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d467e0eab7c97e8c700470433b7adb7 |
| publicationDate |
2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112021000919-A2 |
| titleOfInvention |
chimeric antigen receptors with bcma specificity and uses thereof |
| abstract |
chimeric antigen receptors with bcma specificity and uses thereof. the b cell maturation antigen (bcma) is expressed in malignant plasma cells. the present invention provides bcma-specific chimeric antigen receptors and cells that express such chimeric antigen receptors. in certain embodiments, the modified cells that express the chimeric antigen receptors of the present invention are capable of inhibiting the growth of tumors that express bcma. the modified cells of the invention are useful for the treatment of diseases and disorders in which an immune response that targets a positively regulated or induced bcma is desired and / or therapeutically beneficial. for example, modified cells that express the bcma-specific chimeric antigen receptors of the invention are useful for the treatment of various cancers, including multiple myeloma. |
| priorityDate |
2018-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |