| abstract |
: “ANTIBODIES THAT BIND THE SIGHT INnACID pH ”. The present invention relates to antibodies that specifically bind to the T cell activation suppressor containing domain V immunoglobulin (VISTA) at acidic pH and their use in the treatment of cancer. In some embodiments, antibodies specifically bind to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH. |