http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112020023259-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6c945f182833bcc8718c1244788bc30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5aef6c426a07b053aa061f946ce4f68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73e1811d43cc130de2daafc08fecf8eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2019-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b0d203065b10f08dadc406c62472832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69b87b390968cb91584767e5279d1fa8 |
| publicationDate | 2021-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-112020023259-A2 |
| titleOfInvention | blood stroke biomarkers |
| abstract | Blood Stroke Biomarkers Stroke is a devastating disorder that contributes significantly to the costs of death, disability and health. the current challenge is to prevent late cell death, with concomitant therapy to expand the therapeutic window. a potential diagnostic method for stroke is the use of rna in the blood as a biomarker, which is an emerging field in medicine. in that document, gene expression was explored after the onset of cerebral ischemia in the brain and blood. the study of microarray expression data from macaque monkeys of the brain and blood revealed that ischemic and non-ischemic samples can be distinguished based on their expression profiles, and most highly expressed genes are positively regulated in the ischemic scenario 6 hours after ischemia. a comparison of genes differentially expressed in the brain and blood revealed a significant overlap in gene expression patterns. the data showed that there is a common signature between the ischemic brain and the blood and support the development of blood transcriptomics as a tool for profiling the biopsy transcriptome to characterize patients with ischemic stroke to develop a companion biomarker for the evaluation of neuroprotective drugs in patients. |
| priorityDate | 2018-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 434.