| abstract |
CANCER TREATMENT METHODS. Therapeutic methods and pharmaceutical compositions for the treatment of cancer are described, including a myeloproliferative neoplasm (PMN), including polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis in a human subject. In certain embodiments, the invention includes therapeutic methods of treating an NMP using a Formula (I) or Formula (II) MDM2 inhibitor. |