| abstract |
"PROCEDURES OF C5AR Fused BICYCLIC ANTAGONISTS". The present invention provides, inter alia, compounds of the formulas IA, IB, IC, IIA, IIB and IIC or pharmaceutically acceptable salts thereof which are modulators of the C5a receptor. Pharmaceutical compositions and methods of use are also provided that include the treatment of diseases or disorders involving pathological C5a activation and non-pharmaceutical applications. |