| titleOfInvention |
double-stranded ribonucleic acid agent, cell, vector, pharmaceutical composition, and, methods for inhibiting the expression of 17¿-hydroxysteroid dehydrogenases type 13, for treatment of an individual, for prevention of a symptom in an individual, for risk reduction to develop chronic liver disease, to inhibit steatosis progression, to inhibit the accumulation of lipid droplets |
| abstract |
double-stranded ribonucleic acid agent, cell, vector, pharmaceutical composition, and, methods for inhibiting the expression of 17? -hydroxysteroid dehydrogenases type 13, for treatment of an individual, for prevention of a symptom in an individual, for risk reduction to develop chronic liver disease, to inhibit the progression of steatosis, to inhibit the accumulation of lipid droplets. the invention relates to double-stranded ribonucleic acid (dsrna) compositions targeting the hsd17b13 gene, as well as methods for inhibiting the expression of hsd17b13 and methods for treating individuals who would benefit from reduced hsd17b13 expression, such as individuals with of a disease, disorder or condition associated with hsd17b13, using such dsrna compositions. |