http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112020016927-A2

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filingDate 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0bc9dff4663f152510fc4de76378b16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_749406c5f6a00f73388dbb7143f6c210
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e5088564da8a0cc908ebfff149d0aba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38a6ff7ad7db8eb92b47ae32486f5885
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bd433a47731bcdf2d9769729600d6c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac0672cbeee74da1927b294862388a1f
publicationDate 2020-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-112020016927-A2
titleOfInvention N- (PHENYL) -2- (PHENYL) PYRIMIDIN-4-CARBOXAMIDE DERIVATIVES AND COMPOUNDS RELATED TO HPK1 INHIBITORS TO TREAT CANCER
abstract The present invention relates to N- (phenyl) -2- (phenyl) -pyrimidine-4-carboxamide derivatives and related compounds of formula I as inhibitors of HPK1 (hematopoietic progenitor kinase 1) to treat cancer, such as example, breast cancer, colorectal cancer, lung cancer, ovarian cancer and pancreatic cancer. Preferred compounds are, for example, N- (5-Fluoro-2- (2pyridin-2-yl) pyrrolidin-1-yl) phenyl) -2- (2-fluoro-6-methoxyphenyl) pyrimidine-4-carboxamide - (5-Fluoro-2- (hexahydropyrrolo [3,4-b] pyrrole-1 (2H) -yl) phenyl) -2- (2-fluoro-6-methoxyphenyl) pyrimidine-4-carboxamide.n (I)
priorityDate 2018-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5RCH1
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Total number of triples: 1438.