abstract |
Heteroaryl compounds, for example, a compound of Formula I or IA and pharmaceutical compositions thereof are provided in the present invention. Also provided in the present invention are methods of using it to treat, ameliorate or prevent one or more symptoms of a disorder, disease or condition mediated by a casein kinase 1 (CK1), a kinase associated with the interleukin-1 receptor (IRAK1) or a cyclin-dependent kinase 9 (CDK9). |