| abstract |
Methods and materials for the prevention and modulation of atherosclerosis. In particular, small peptides that are able to interact with CD40, thus interfering with the ability of CD40 to interact with CD154, which confers inflammation and atherosclerosis. The use of these peptides to reduce atherosclerosis and, in particular, the autoimmune inflammatory response, which can be a driving factor for it. The use of these short peptides to lower LDL cholesterol. Methods and materials for detecting CD40-expressing T cells (Th40 cells). Methods and materials for the prevention, modulation, reduction and / or reversal of type 2 diabetes and autoinflammatory diseases. In particular, small peptides that are able to interact with CD40, thus interfering with the ability of CD40 to interact with CD154, which leads to inflammation and type 2 diabetes. The use of these peptides to reduce type 2 diabetes and, in particular, the inflammatory response autoimmune, can be a driving factor of it. The use of these short peptides to decrease IL2, INF¿ and IL17a. The use of these peptides to increase the glucose transport protein (GLUT4). Methods and materials for detecting CD40-expressing T cells (Th40 cells). |