| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_54bf342945ea4d519875cac777cac2ea |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2820-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-14043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-105 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
| filingDate |
2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_416bc188a7c56d7e1bf5a290308e4118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff6e3a121617c0083695a85b29cc5652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a998844a5c98c6f1738a83e66468107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_957bb8bc9468398dcf5e98600124083d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_597fbbdb2ef1599da1e6c08c092de2cb |
| publicationDate |
2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112020013319-A2 |
| titleOfInvention |
closed-ended dna vectors obtainable from cell-free synthesis and process to obtain cedna vectors |
| abstract |
The present invention relates to methods for synthetic and cell-free synthesis of DNA vectors, particularly closed-ended DNA vectors (e.g., cedna vectors) that have linear and continuous structure for delivery and expression of a transgene. The present invention relates to an in vitro process for producing closed-ended DNA vectors, corresponding DNA vector products produced by the methods and uses thereof, and oligonucleotides and kits useful in the process of the invention. DNA vectors produced using the methods described herein are free from unwanted side effects due to contaminants introduced during production into cell lines, for example bacterial or insect cell lines. further provided herein are methods and cell lines for reliable gene expression in vitro, ex vivo and in vivo using the cedna vectors synthesized using the methods described herein. |
| priorityDate |
2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |