| abstract |
a compound capable of being used as a tumor inhibitor, a method of preparing it and applying it. the compound has a structure represented by the general formula i; a stereoisomer, an enantiomer, a racemate, a cis / trans isomer, a tautomer and an isotopic variant of the compound are comprised; the compound can be used separately or in combination with other drugs to treat tumors or inflammatory diseases or to treat other disorders or diseases mediated by the activity of mdm2 and / or mdm4 and shows prominent curative activity. |