| abstract |
a method for preparing a mucoadhesive film containing vardenafil or a pharmaceutically acceptable salt of vardenafil by mixing, in an aqueous liquid carrier, vardenafil or a pharmaceutically acceptable salt of vardenafil, a c3-c12 polyol and a ph regulating agent, to obtain a composition liquid with a pH of at least 4.2; mixing the liquid composition with a monovalent cation alginate salt or a mixture of these salts, distributing the obtained composition on a solid surface; and allow the composition to dry. a mucoadhesive film containing vardenafil or a pharmaceutically acceptable salt of vardenafil, its use for treating sexual dysfunction. |