| abstract |
the invention relates to the compounds of the formula (i): (i) in which r1, r2, r3, r4, l and a are defined in the description and claims or pharmaceutically acceptable salts thereof which exhibit inhibitor activity of ktor kinase. the invention also relates to pharmaceutical compositions, including a compound of formula (i) or a pharmaceutically acceptable salt thereof, and the use of a compound of formula (i) or a pharmaceutically acceptable salt thereof in therapy, including in treatment of a disease or condition for which an inhibitor of mtor kinase activity is indicated and, in particular, in the treatment of idiopathic pulmonary fibrosis. |