abstract |
the present invention relates to friablestable compositions suitable for iontophoretic transdermal delivery of a triptan compound, comprising: - a salt of a triptan compound, preferably sumatriptan succinate, - a polyamine, - a dicarboxylic acid, and - water or an aqueous solvent mixture, in which this composition is free of monocarboxylic acids. the invention further relates to the use of the composition as an integral component of an iontophoretic adhesive, preferably as an anodic reservoir of the adhesive. |