http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112020008791-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b698c934c4b923aa5bc9e441eb68d5d |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188 |
filingDate | 2018-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f050cdb24c419a5f6e4b930f0f120e7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4679cd85b39518e2b414c6538f263cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb2e068a054ff8a616664f18df22bd62 |
publicationDate | 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BR-112020008791-A2 |
titleOfInvention | imipridones for gliomas |
abstract | these are imipridones that selectively modulate receptors coupled to class a g protein (gpcrs), such as the dopamine d2 type subfamily, and are useful for treating conditions and disorders in need of such modulation, such as cancers. specifically, the cancer involves a midline brain structure, a cancer with a h3 histone mutation, or both. in addition, methods are provided to identify whether a subject with these conditions is likely to be responsive to a treatment regimen, such as administration of imipridone. in addition, methods are also provided to assess the effectiveness of a treatment regimen, such as administering imipridone, monitoring or providing a prognosis for a subject with these conditions. |
priorityDate | 2017-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1673.