| abstract |
the present invention relates to new dihydropyridine derivatives of formula (i): as modulators of nuclear receptors selected from androgen receptor and glucocorticoid receptor, to processes for their preparation, to pharmaceutical compositions comprising said compounds and to the use of them for the production of a medicine for the treatment of pathological conditions or diseases that can improve by modulating the androgen receptor and / or glucocorticoid receptor, selected from cancer, metastatic cancers, benign prostatic hyperplasia, ovary syndrome polycystic (sopc), hair loss, hirsutism, acne, hypogonadism, muscle wasting diseases, cachexia, cushing's syndrome, weight gain induced by antipsychotic drugs, obesity, post-traumatic stress disorder and alcoholism. |