| abstract |
the present invention relates to a compound of formula (i), wherein p1, p3, p4 and p5 are amino acid residues or structures similar to amino acids. the invention also relates to a compound of formula (i) for its use as a caspase-2 inhibitor and for its therapeutic use. it also concerns the use of a compound of formula (i) as an activity-based probe to selectively detect caspase2 activity. |