| abstract |
the present invention relates to cytolytic bi-component protein complexes consisting of a plurality of molecules from a member of the aegerolysin family and a plurality of molecules from a member of the macpf superfamily, and particularly to their use for control from a plant pest, such as to control the colorado potato beetle (leptinotarsa decemlineata) or western corn root weevil (dieabrotica virgifera virgifera). more specifically, the invention relates to cytolytic bi-component protein complexes formed by a plurality of molecules of one of the aegerolysins ostreolysin a6 (olya6), pleurotolysin a2 (plya2) and erilisin a (erya) with a plurality of molecules of pleurotholysin b (plyb) or similar proteins, which have been shown to be toxic to the pest insects mentioned above. |