http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112020004977-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-572 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2018-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ed1cd8d9772f15459a361ad3bac6b32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad4ef76bfd7bb24c8c330fbea8de97a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_418948c5441785823e03c4446c2ad404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b0a802a2dcc79d8b91d8b753b59c632 |
| publicationDate | 2020-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-112020004977-A2 |
| titleOfInvention | bispecific antigen binding molecules that bind staphyocococcus target antigen and complement component and uses thereof |
| abstract | according to certain embodiments, the present invention provides bispecific antigen binding molecules comprising a first antigen binding domain that specifically binds a target antigen of the staphylococcus species and a second antigen binding domain that binds a complement component. in certain embodiments, the bispecific antigen binding molecules of the present invention are able to bind to the target antigen of the staphylococcus species with an ec50 of about 10nm or less and / or are capable of promoting complement deposition in staphylococcus species with an ec50 of about 10nm. the antibodies of the description are useful for the treatment of diseases in which the inhibition or reduced growth of a species of staphylococcus is desired and / or therapeutically beneficial, for example, for the treatment of staphylococcal infections including a skin infection, cellulitis, pneumonia , meningitis, urinary tract infection, toxic shock syndrome, endocarditis, osteomyelitis, bacteremia or sepsis, or to prevent or treat a staphylococcus infection that occurs as a result of a surgical procedure. |
| priorityDate | 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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