| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a188cd8a5bcf631dc924b383b8d5594 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2018-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_217a668601f5b2f58432335bc6f7d477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_def88a87c0cd06895a6e9588632691af |
| publicationDate |
2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112020003988-A2 |
| titleOfInvention |
agonistic antibodies cd40 |
| abstract |
the present invention relates to humanized monoclonal antibodies or their antigen-binding fragments that specifically bind to the human cd40 receptor and induce cd40 signaling independent of crosslinking of the fc¿ mediated cd40 receptor. the antibodies of the present invention bind to a cd40 epitope that overlaps the cd40 ligand epitope and can activate human apcs. the present invention also provides compositions comprising said antibodies and uses for antibodies and compositions in the treatment of cancer patients. |
| priorityDate |
2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |