| abstract |
the present invention relates to the fields of medicinal chemistry, biotechnology and pharmaceuticals. the invention provides compositions comprising one or more collagen mimetic peptides, optionally linked to one or more therapeutic compounds or one or more imaging compounds, for use in methods of treatment, prevention, improvement, cure and diagnosis of certain diseases and physical disorders in humans and veterinary animals, as well as methods of making that composition. the invention also provides medical devices comprising one or more of these compositions of the invention. the invention also provides methods of using such compositions and devices in the treatment and diagnosis of certain diseases and physical disorders in humans and veterinary animals, including eye diseases or disorders, skin diseases or disorders, certain types of cancer, particularly intraluminal cancers, diseases or gastrointestinal disorders, diseases or disorders of the genitourinary tract, fibrotic diseases or disorders and rheumatic diseases or disorders. |