Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_374bd30b140c412aedda14571cbbc4a7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-52 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 |
filingDate |
2018-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b01a06835c3d74f194eae8596a5d688 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fc7e89b2baefa40d473739f4a79ad29 |
publicationDate |
2020-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
BR-112019019589-A2 |
titleOfInvention |
process for the preparation of a sulfonamide structured kinase inhibitor |
abstract |
the present invention relates to an improved process for the preparation of a sulfonamide structured kinase inhibitor, namely n- (2 ', 4'-diflĂșor-5- (5- (1-methyl-1h-pyrazol-4-yl ) -1h-benzo [d] imidazol-1-yl) - [1,1'-biphenyl] -3-yl) cyclopropanesulfonamide (1a) and pharmaceutically acceptable salts thereof. compound of formula (1a) is a selective inhibitor of the fgrf / vegfr kinase families and is useful in the treatment of cancer. |
priorityDate |
2017-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |