http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112019018743-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79b4e51ee2130481fc3aab197ebe70c2 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
filingDate | 2018-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b24ac55d04576fcdc72f74a2d823721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7fe0f9ce3750730f3e9a93daa1a5871 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10f144fadaec1191fcd8a15e3535ad60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b04c8a476742ac6d62c4601734bb862 |
publicationDate | 2020-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BR-112019018743-A2 |
titleOfInvention | methylation classifier for the detection of invasive hpv-induced cancers, non-hpv-induced gynecological and anogenital cancers and their high-grade precursor lesions |
abstract | the invention relates to the method for detecting high-grade precancerous lesions induced by hpv, invasive cancers induced by hpv and non-hpv-induced gynecological and anogenital cancers, said method comprises the detection of a methylation classifier consisting of the lhx8 genes, ascl1 and st6galnac5 and their regulation sequence in a cell, whereby hypermethylation indicates the presence of precursor lesions induced by hpv with invasive potential, invasive cancers induced by hpv and gynecological and anogenital cancers not induced by hpv. the invention further comprises the use of the methylation classifier consisting of the lhx8, ascl1 and st6galnac5 genes and their regulation sequences in such a method, and in a test kit to detect the methylation of lhx8, ascl1 and / or st6galnac5. |
priorityDate | 2017-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.