| abstract |
ifn-¿-inducible (irtca) -changing regulatory t cell convertible antibodies and antigen-binding fragment are provided that bind to an activation-inducible tnfr polypeptide (aitr). various in vitro and in vivo antibody-related methods and compositions described herein are also provided. methods include, for example, changing the cytokine secretion of t cells in vivo or in vitro and prevention and / or therapeutic treatment of cancer using an irtca antibody or a fragment thereof. |