abstract |
the present invention relates to the field of biomedicine and, in particular, to the field of therapeutic nucleic acids. the present invention provides artificial nucleic acids, in particular, encoding proteins associated with crispr. a (pharmaceutical) composition and kit of parts comprising the same are also provided. further, the present invention relates to the artificial nucleic acid, composition (pharmaceutical) or kit of parts for use in medicine, and in particular in the treatment and / or prophylaxis of diseases condescending to treatment with associated crispr proteins. |