| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44367c7b17bf07d2d403f117a3fe1a97 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-186
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate |
2018-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99a35cd4a8a0c53c197078522f0e82a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_394c28a53270a19bf197cdd48f863693
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00f0705e9f210f05d2102499102f6764
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ba8ec2d79b8563028e43ab47ca999bc |
| publicationDate |
2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112019014408-A2 |
| titleOfInvention |
nasal composition of tapentadol |
| abstract |
an intranasal composition as a unit dose, comprising tapentadol or a pharmaceutically acceptable salt thereof in an amount that is equivalent to about 19.3 mg of tapentadol in free base; and at least one nasal carrier. after intranasal administration to humans, the average cmax value of tapentadol achieved by said unit dose is equivalent to or greater than the average cmax value of tapentadol achieved by oral administration to humans of an immediate release composition comprising tapentadol or a salt pharmaceutically acceptable product, in an amount that is equivalent to 50 mg of tapentadol in free base. |
| priorityDate |
2017-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |