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publicationDate 2019-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-112018075823-A2
titleOfInvention n- (2- (2- (dimethylamino) ethoxy) -4-methoxy-5 - ((4- (1-methyl-1h-indol-3-yl) pyrimidin-2-yl) amino) phenyl) pharmaceutical salts acrylamide and its crystalline forms
abstract n- (2- (2- (dimethylamino) ethoxy) -4-methoxy-5 - ((4- (1-methyl-1h-indol-3-yl) pyrimidin-2-yl) amine) phenyl) crystalline forms Acrylamide (1) and its pharmaceutically acceptable salts and compositions useful for the treatment or prevention of diseases or clinical conditions mediated by mutant forms of the epidermal growth factor receptor (eg epidermal growth factor receptor), such as various cancers, are disclosed.
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