abstract |
The invention relates to a novel method for treating liquid and solid cancers in a mammal, including humans, in which methioninase is administered prior to asparaginase. The invention also encompasses the use of a dietary methionine deprivation possibly combined with methioninase administration prior to asparaginase treatment. methioninase and asparaginase may be used, in particular in free form, pegylated or erythrocyte encapsulated form. |