http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-112018008681-A2

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filingDate 2016-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbc3f5d61cd0318ed2dc9a4eb912a879
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publicationDate 2018-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-112018008681-A2
titleOfInvention novel polypeptides with improved proteolytic stability, and methods for preparing and using them
abstract The present invention includes methods for improving the proteolytic stability of a polypeptide, comprising alkylating at least one selected from the group consisting of an n-terminal amino group, the nh group of the first n-terminal internal amide bond, another primary amino group, a thiol group and a thioether group in the polypeptide. The present invention further includes polypeptides incorporating such chemical modifications.
priorityDate 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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