| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33c922e05f6133b7d72dbb849d77487d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-32634
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0017 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0016
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
| filingDate |
2016-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d19f69b9adc406bcdcbb0edfbd8cef6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c50bed49d010b609612ba6a8903483b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77b8f1b74cdc66d6bc812024652e2b57 |
| publicationDate |
2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112018005291-A2 |
| titleOfInvention |
multi-dose combined vaccine composition |
| abstract |
The present invention relates to a multi-dose immunogenic composition for a multivalent combined vaccine, wherein (i) the multivalent combined vaccine contains a whole cell pertussis (wp) vaccine or an acellular pertussis (ap) vaccine and a sabin inactivated polio vaccine (sipv); and (ii) the composition contains 2-phenoxyethanol (2-pe) and formaldehyde (hcho) as preservatives; and a method for preparing an immunogenic composition at various doses for a multivalent combined vaccine. It has been confirmed that the combination of 2-phenoxyethanol and formaldehyde according to the present invention is an excellent preservative capable of maintaining antimicrobial ability and that it can be effectively used to provide a multi-dose composition while maintaining the antimicrobial ability of the combined vaccine. Thus, the composition of the present invention can be effectively used in the combined dose vaccine industry. |
| priorityDate |
2015-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |