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filingDate 2016-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f503bad8b43b2d1276cde234ee67c6a
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publicationDate 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-112017026859-B1
titleOfInvention method of preparing cross-linked polysaccharide materials
abstract method of preparation of crosslinked polysaccharide materials and material. The invention discloses a method for the preparation of crosslinked polysaccharide materials using electromagnetic radiation in aqueous solution containing polysaccharides with a photo-removable protective group of attached carbamate (ppg with the group -nh-co-o-) and a polysaccharide containing an aldehyde group - cho. the crosslinking process itself is carried out through a condensation reaction of the photochemically released amino group (-nh2) with the aldehyde group (-cho) forming an imine-type bond (n=ch-). both processes proceed simultaneously and can be carried out under physiological conditions. the advantage of the suggested solution is the temporal and spatial control of the crosslinking which allows the preparation of advanced materials for tissue engineering where the crosslinking density and mechanical properties in the material structure can be adapted.
priorityDate 2015-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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