abstract |
TETRAHYDRONAPHTHALENE DERIVATIVES WHICH INHIBIT MCL-1 PROTEIN. Presented herein are myeloid cell leukemia protein 1 (Mcl-1) inhibitors, methods for their preparation, related pharmaceutical compositions, and methods of using the same. For example, compounds of Formula I, (I) and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds are disclosed herein. The compounds and compositions presented herein can be used, for example, in the treatment of diseases or conditions, such as cancer. |