| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ee0da6543d4d16f0634e75baf2d0d58 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-01064
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-00 |
| filingDate |
2015-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_727d8ce0401c6792f54fdcb73af159b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_632acd09cf27c8c15d86cce83ba28092
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a9eaf0cba1d7c88640caa93cd28830c |
| publicationDate |
2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BR-112017001909-A2 |
| titleOfInvention |
proteins, pharmaceutical composition, nucleic acid, vectors, cell, gene therapy method, method for treating a condition, use of a vector, and use of a mutant mammalian protein |
| abstract |
mutant mammalian rpe65 proteins and portions thereof, and mutant-encoding nucleic acids, for use in treating a condition related to retinal degeneration in a subject, mutant mammalian rpe65 proteins or portions thereof having isomerohydrolase activity. a method of gene therapy for treating a condition related to retinal degeneration in a mammalian subject in need of such treatment, comprising administering to said subject a therapeutically effective amount of a vector comprising a nucleic acid encoding a mutant mammalian rpe65 protein or a portion of it. A method for treating a condition related to retinal degeneration in a subject in need of such treatment, comprising administering to the subject a therapeutically effective amount of at least one of a mutant mammalian rpe65 protein or a portion thereof. |
| priorityDate |
2014-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |