| abstract |
5-BENZYLISOQUINOLINE DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISEASES. The invention relates to new isoquinoline derivatives of formula (I), their synthesis, and their use in the prevention and/or treatment of pathologies resulting from the activation of the RhoA/ROCK reaction series and the phosphorylation of the chain light myosin. X represents a -C(=O), -CH(OH)- or -CH 2 - group, and the other substituents represent various groups such as those defined in claim 1. |