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publicationDate 2017-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BR-112016002651-A2
titleOfInvention compound, pharmaceutically acceptable salt of a compound, pharmaceutical composition, combination, pharmaceutical formulation, methods for exterminating a mycobacterium and / or inhibiting mycobacterial replication, and for treating an infection and disease, and use of a compound
abstract compounds of formula ii, wherein x is selected from chlorine, fluorine, bromine and iodine, each of r1 and r2 is independently selected from h, -ch3, -ch2ch3, -ch2ch2ch3 or -ch (ch3) 2; Compositions thereof are provided, their use in therapy, including their use as antimicobacterial agents, for example, in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds.
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